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Annual Meeting Schedule: Schedule

Day 1, July 28, 2016

(E) Lectures in English (J) Lectures in Japanese

14:00 - 14:30

JSGCT Chairman's Lecture (E) Hall-1

“Mission of JSGCT for gene therapy prosperity in future”

Chair: Jun Yoshida ( Emeritus Director of Sakura General Hospital)
Speaker: Yasufumi Kaneda(Graduate School of Medicine, Osaka University)


14:30 - 15:10

Educational Lecture I (E) Hall-1

“Nobel treatment strategies including gene therapy for genetic neurological disorders ”

Chair: Toya Ohashi (The Jikei University School of Medicine)
Speaker: Yoshikatsu Eto (Advanced Clinical Research Center, Institute of
              Neurological Disorders, Kanagawa)


15:10 - 15:50

Educational Lecture II (E) Hall-1

“Gene therapy for X-linked adrenoleukodystrophy and metachromatic leukodystrophy”

Chair: Takashi Shimada (Nippon Medical School)
Speaker: Patrick Aubourg(INSERM, France)


16:00 - 18:10

Symposium-I: ICFHGTGD-JSGCT Joint Symposium “Genetic disease” (E) Hall-1

Chairs: Torayuki Okuyama (National Center for Child Health and Development)
           Masashi Onodera (National Center for Child Health and Development)

  1. “Gene therapy for AADC deficiency: toward a standard therapy”
       Speaker: Wuh-Liang Hwu (National Taiwan University Hospital)
  2. Ex-vivo gene therapy, as a promising approach for the treatment of central nervous system of Mucopolysaccharidosis type II murine model”
       Speaker: Hiroshi Kobayashi (The Jikei University School of Medicine)
  3. “Hematopoietic stem cell gene therapy for Wiskott-Aldrich syndrome”
       Speaker: Toru Uchiyama (National Center for Child Health and
                     Development)
  4. “Development and clinical application of gene therapy using AAV for child neurological diseases”
       Speaker: Takanori Yamagata (Jichi Medical University)
  5. “Gene therapy for inherited retinal degenerative diseases ”
       Speaker: Yasuhiro Ikeda (Graduate School of Medical Sciences, Kyushu
                     University)

Day 2, July 29, 2016

(E) Lectures in English (J) Lectures in Japanese

08:30 - 09:50

Symposium-II: Regulatory Science (J) Hall-1

Chairs: Akihiro Kume (Jichi Medical University)
           Teruhide Yamaguchi (Nihon Pharmaceutical University)

  1. “AMED programs to promote innovative drug development”
       Speaker: Yoshiro Meguro (Japan Agency for Medical Research and
                     Development)
  2. “AMED support for medical R&D projects”
       Speaker: Jun Matsumoto (Japan Agency for Medical Research and
                     Development)
  3. “Regulatory perspective on cell and gene therapy products”
       Speaker: Daisaku Sato (Pharmaceuticals and Medical Devices Agency)
  4. “Introduction of pharmaceutical affairs consultation on R&D strategy and its effective utilization”
       Speaker: Hisashi Koike (Pharmaceuticals and Medical Devices Agency)

08:30 - 09:10

Technical Seminar: AAV, lentivirus vector (J) Hall-2

Chair: Hiroyuki Miyoshi (Keio University School of Medicine)

  1. “Attractive characteristics of self-complementary AAV vectors and improved methods for efficient production”
       Speaker: Takashi Okada (Nippon Medical School)
  2. “Clinical use of lentiviral vectors”
       Speaker: Hiroyuki Miyoshi (Keio University School of Medicine)
  3. “The application of genome editing for gene therapy”
       Speaker: Yumi Kanegae (The Jikei University School of Medicine)

09:50 - 11:00

Main Symposium (E) Hall-1

Chairs: Yasufumi Kaneda (Graduate School of Medicine, Osaka University)
           Yasutomo Nasu (Medical School, Okayama University)

  1. “Investigating stem cell biology and therapeutic potential in the rhesus macaque model”
       Speaker: Cynthia E. Dunbar (NIH, ASGCT President)
  2. “Improved daylight vision in mice following gene therapy to increase the speed of rod photoreceptors”
       Speaker: Robin Ali (UCL Institute of Ophthalmology, ESGCT President)

11:00 - 11:40

“President's Special Program with AMED, Ministry of Health, Labour and Welfare” (J) Hall-1

  1. “AMED develops medical arts for patients with rare and undiagnosed diseases”
       Chair : Toshiyoshi Fujiwara (Medical School, Okayama University)
       Speaker: Makoto Suematsu (Japan Agency for Medical Research and
                     Development)
  2. TITLE
       Chair: Shigetaka Asano (Professor Emeritus, The University of Tokyo, and
                 Waseda University)
       Speaker: Kazuhiko Mori (Ministry of Health, Labour and Welfare)

11:40 - 12:00

Presidential Lecture (E) Hall-1

“Current treatment and gene therapy for lysosomal storage diseases”

Chair: Yoshikatsu Eto (Advanced Clinical Research Center, Institute of Neurological
          Disorders, Kanagawa)
Speaker: Toya Ohashi (The Jikei University School of Medicine)


13:00 - 13:40

Educational Lecture-III (E) Hall-1

“TGF-β signaling: Mechanisms of action and clinical application”

Chairs: Izumu Saito (The Institute of Medical Science, The University of Tokyo)
           Yutaka Hanazono (Jichi Medical University)
Speaker: Kohei Miyazono (Graduate School of Medicine, University of Tokyo)


13:00 - 13:40

Educational Lecture-IV (E) Hall-2

“Rare variants in human diseases”

Chairs: Eriko Uchida (National Institute of Health Sciences)
           Hiroshi Kobayashi (The Jikei University School of Medicine)
Speaker: Naomichi Matsumoto (Yokohama City University Graduate School of
              Medicine)


13:40 - 15:30

International Symposium (E) Hall-1

Chairs: Noriyuki Kasahara(University of Miami, USA)
           Masato Yamamoto(University of Minnesota, USA)

  1. “Modulation of the local tumor micro-environment by LV-mediated expression of IL-12 in primary AML cells”
       Speaker: Jeffrey Medin (Medical College of Wisconsin, USA)
  2. “A robust production platform: A basic requirement for successful gene therapy products”
       Speaker: Harald Petry (UniQure, The Netherlands)
  3. “Genome editing in primary human cells and organs: Towards the goal of engineering genetic cures”
       Speaker: Michael C. Holmes (Sangamo bio, USA)
    *Changed to the below:↓
    “ZFN-Mediated Genome Editing in the Liver –Towards Correcting Lysosomal Storage Diseases”
       Speaker: Thomas Wechsler (Sangamo BioSciences, Inc., USA)
  4. “Ascending dose trials of a retroviral replicating vector (Toca 511) in patients with recurrent high-grade glioma: clinical update, molecular analyses, and proposed mechanism of action”
       Speaker: Douglas J. Jolly (Tocagen Inc., USA)

13:40 - 14:40

Symposium-III: Genome editing (E) Hall-2

Chairs: Konosuke Mitani (Saitama Medical University)
           Yumi Kanegae (The Jikei University School of Medicine)

  1. “Structure-based development of genome-editing tool, CRISPR-Cas9 towards medical applications”
       Speaker: Osamu Nureki (Graduate School of Science, The University of
                     Tokyo)
  2. “Genome editing gene therapy for Duchenne muscular dystrophy”
       Speaker: Akitsu Hotta (Center for iPS cell Research & Application (CiRA),
                     Kyoto University)
  3. “Recent progress and remaining challenges in therapeutic genome editing”
       Speaker: Konosuke Mitani (Saitama Medical University)

15:40 - 17:40

Symposium-IV: Cancer (E) Hall-1

Chairs: Tomoki Todo (The Institute of Medical Science, The University of Tokyo)
           Kenzaburo Tani (The Institute of Medical Science, The University of Tokyo)

  1. “Next-generation telomelysin: multifunctional telomerase-specific oncolytic adenovirus armed with thewild-type p53 tumor suppressor gene”
       Speaker: Toshiyoshi Fujiwara (Medical School, Okayama University)
  2. “Clinical trials of oncolytic HSV-1 G47Δ for patients with glioblastoma”
       Speaker: Yasushi Ino (The Institute of Medical Science, The University of
                     Tokyo)
  3. “Systemic delivery of Enadenotucirev, a Group B oncolytic adenovirus for the treatment of cancer”
       Speaker: Kerry Fisher (Psioxus)
  4. “Talimogene laherparepvec: Harnessing herpes virus for the treatment of advanced melanoma”
       Speaker: Swami Murugappan (Amgen Inc.)
  5. “Development of new oncolytic virotherapy for malignancies”
       Speaker: Kenzaburo Tani (The Institute of Medical Science, The University
                     of Tokyo)

Day 3, July 30, 2016

(E) Lectures in English (J) Lectures in Japanese

08:30 - 11:30

The 2nd International Symposium of the Asia-Pacific Gene Therapy Consortium (E) Hall-1

*) This Symposium is free of charge to attend but limited to those who have paid their JSGCT2016 Annual Meeting's registration fee.

Chairs: Chae-Ok Yun (College of Engineering Hanyang University, Seoul, Korea)
           Masatoshi Tagawa (Chiba Cancer Center Research Institute)

  1. “AAV vectors as tools for liver-targeted gene therapy: efficacy and safety”
       Speaker: Ian Alexander Australia (Gene Therapy Research Unit,
                     Children's Medical Research Institute and the Sydney Children's
                     Hospitals Network, Sydney, Australia)
  2. “Multicenter randomized phase II/III clinical trial of a recombinant human endostatin adenovirus for cancer gene therapy”
       Speaker: Wenlin Huang, Shuai Chen, Ranyi Liu,
                     Jiangxue Wu(Sun Yat-Sen University Cancer Center, China)
  3. “Smart nanoparticles for drug, gene and gas delivery”
       Speaker: Won Jong Kim (Pohang University of Science and Technology
                     (POSTECH), Pohang, Korea)
  4. “Gene therapy for central nervous system disorders”
       Speaker: Shin-ichi Muramatsu (Jichi Medical University)

08:30 - 10:30

Symposium-V: Cardiovascular Diseases (E) Hall-2

Chairs: Ryuichi Morishita (Graduate School of Medicine, Osaka University)
           Yoshikazu Yonemitsu (Graduate School of Medical Sciences,
           Kyushu University)

  1. “Wnt11 gene therapy with adeno-associated virus 9 improves recovery from myocardial infarction”
       Speaker: Toyoaki Murohara (Nagoya Univeristy Graduate School of
                     Medicine)
  2. “Clinical application of human iPS cells for the treatment of patients with severe congestive heart failure”
       Speaker: Keiichi Fukuda (Keio University School of Medicine)
  3. “Current status of clinical development of human FGF-2-expressing recombinant sendai virus vector (DVC1-0101) to treat peripheral arterial disease”
       Speaker: Yoshikazu Yonemitsu (Graduate School of Medical Sciences,
                     Kyushu University)
  4. “Gene therapy for lymphedema”
       Speaker: Yukihiro Saito (Asahikawa Medical University)
  5. “The development of IL-17A vaccine”
       Speaker: Hiroshi Koriyama (Graduate School of Medicine, Osaka
                     University)
  6. “Pivotal roles of inflammatory factors in vascular disease and its specific regulation”
       Speaker: Jun-ichi Suzuki (Graduate School of Medicine, University of
                     Tokyo)

10:40 - 12:00

Symposium-VI: JSRM-JSGCT Joint Symposium “Cell Therapy” (E) Hall-2

Chairs: Makoto Otsu (The Institute of Medical Science, The University of Tokyo)
           Tokiko Nagamura (The Institute of Medical Science, The University of Tokyo)

  1. “Intravenous transplantation of autologous mesenchymal stem cells derived from bone marrow into stroke patient”
       Speaker: Osamu Honmou (Sapporo Medical University)
  2. “Dedifferentiated fat cells as a new cell source for therapeutic angiogenesis and regenerative medicine”
       Speaker: Taro Matsumoto (Nihon University School of Medicine)
  3. “Umbilical cord is a rich source of mesenchymal stromal cells for cell therapies”
       Speaker: Tokiko Nagamura (The Institute of Medical Science, The
                     University of Tokyo)

11:30 - 12:00

Special Lecture (E) Hall-1

“Gene therapy for RPE65-mediated inherited retinal disease”

Chair: Takashi Okada (Nippon Medical School)
Speaker: Daniel Chung(Spark Therapeutics, Inc.)


13:00 - 14:50

Symposium-VII: JCA-JSGCT Joint Symposium “Cancer Immunotherapy” (E) Hall-1

Chairs: Keiya Ozawa (The Institute of Medical Science, The University of Tokyo)
           Koji Tamada (Yamaguchi University Graduate School of Medicine)

  1. “New era of cancer immunotherapy begins: A role of gene modified cell therapy”
       Speaker: Koji Tamada (Yamaguchi University Graduate School of Medicine)
  2. “Clinical study of novel adoptive immunotherapy using gene-modified autologous lymphocytes to express WT1 specific T-cell receptor against myeloid leukemia”
       Speaker: Hiroshi Fujiwara (Ehime University Graduate School of Medicine)
  3. “Clinical development of CD19-CAR therapy in patients with B-cell malignancy”
       Speaker: Ken Omine (Jichi Medical University)
  4. “Future perspectives of cancer immunotherapy: Towards personalized combination cancer immunotherapy”
       Speaker: Yutaka Kawakami (Keio University School of Medicine)

13:00 - 14:50

Symposium-VIII: Neurological and Muscle Disease (E) Hall-2

Chairs: Shin-ichi Muramatsu (Jichi Medical University)
           Hideki Mochizuki (Graduate School of Medicine, Osaka University)

  1. “Surgical coverage of the putamen in Parkinson’s disease with AAV2-AADC using MRI-guided convective delivery”
       Speaker: Krystof Bankewicz (University of California)
  2. “Gene therapy to conquer spinocerebellar ataxia”
       Speaker: Hitoshi Okazawa (Tokyo Medical and Dental University)
  3. “Targeting therapy for sporadic ALS”
       Speaker: Shin Kuwak (Graduate School of Medicine, University of Tokyo)
  4. “Antisense oligonucleotide therapy for neurological and neuromuscular disorders”
       Speaker: Masayuki Nakamori (Graduate School of Medicine, Osaka
                     University)

JSGCT:Japan Society 
of Gene and Cell Therapy

Secretariat Office

Division of Gene Therapy,
Research Center for Medical Sciences
Department of Pediatrics
The Jikei University School of Medicine

3−25−8 Nishi-Shinbashi, Minato-ku,
Tokyo 105-8461, Japan
E-mail: jsgct2016@jsgt.jp
Fax: +81-3-3433-1230

Inquiry:

E-mail: jsgct2016@jsgt.jp
Fax: +81-43-306-5664
JSGCT Administrative Office

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